DTI – Diffusion Tensor Imaging

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What is Quantitative DTI?

Quantitative DTI, or Diffusion Tensor Imaging, is an objective and particularly effective method for detecting nerve damage in the brain caused by concussions (mild Traumatic Brain Injury or mTBI).

How does Quantitative DTI Work?

Quantitative DTI measures water molecules as they move along the brains nerve pathways. In the brain, nerve cells are called “axons” and water moves in a specific direction along these pathways. Diffusion Tensor Imaging is a method in which we can watch how water moves along the nerves or what is called FA or fractional anisotropy. If a disruption in the water pathway is detected, we know that there is an injury or damage in that specific area of the brain.

The best way that Quantitative DTI testing can be performed is to have a powerful 3.0T MRI system with specific advanced neurological software and data processing capabilities. Most facilities in the Gulf South region offer only 1.5T MRIs. By using this powerful 3.0T MRI machine, with the necessary software and professional expertise, radiologists segment brain DTI scans into 48 distinct areas to examine the white matter of the brain looking for nerve damage.

Doctors Imaging DTI Program

Dr. Edward Soll, along with a team of MRI and other neuro-scientific experts, has developed the only quantitative Diffusion Tensor Imaging (qDTI) program currently operating in the Gulf South. In consultation with MRI physicists and analytical/statistical PhDs from Harvard, UCLA, the University of New Mexico and Johns Hopkins Medical Schools, Dr. Soll has embraced the MR imaging of the white matter microstructure in the brain and currently evaluates patients suspected of having mild traumatic brain injury (mTBI) with debilitating post-concussion syndromes. In July 2017, Dr. Soll affiliated with MINDSET, the consulting group of the Mind-Research Network at the University of New Mexico in Albuquerque, expanding control group analytics and allowing for age and gender statistical integrity. These methods, combined with NeuroQuant, a volumetric analysis from CorTechs Labs, also allow for investigation of memory loss and Early Onset Alzheimer’s Disease (EOAD). Dr. Soll provides statistically valid data covering 48 individual regions of the brain offering vital information to neurologists, neuro-psychiatrists and neuro-psychologists, allowing them to have objective anatomic correlations for patients suffering from random onset or post-injury memory loss, cognitive, emotional and executive dysfunction. His work has been helpful in evaluating hundreds of patients experiencing difficulties associated with vehicular and industrial accidents as well as explosions and athletic injuries. Through his affiliation with the Tulane Institute of Sports Medicine, he serves as a consultant to the NFL Players Trust. The vast majority of patients he has studied have had earlier normal routine MRI and CT studies. qDTI testing is performed on a 3.0T Siemens MRI system operated at Doctors Imaging in Metairie, LA, just minutes from the New Orleans International Airport. Dr. Soll evaluates white matter injury by determining if a patient’s individual FA (fractional anisotropy) deviates from the normal control subject data collected for Doctors Imaging.

If you have questions or concerns regarding a concussion injury or memory loss or wish to schedule an appointment for a Quantitative DTI at Doctors Imaging, just call 504-883-8111 or fill out the Request Appointment form.